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Neuroimaging Clin N Am. 2013 Nov;23(4):781-98. doi: 10.1016/j.nic.2013.03.019. Epub 2013 May 31.

Arterial ischemic stroke in children.

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Division of Interventional Neuroradiology and Cranial Base Surgery, Departments of Radiology, Neurosurgery, and Otolaryngology, University of Michigan Health System, UH B1D 328, 1500 East Medical Center Drive, Ann Arbor, MI 48109-5030, USA. Electronic address:


Acute ischemic stroke affects 3.3 of 100,000 children per year. The causes of AIS in children can be broadly divided into the following 6 categories: cardiac disese, sickle cell disease, moyamoya, arterial dissection, other arteriopathies, and other causes. Approximately 24% of the cases are classified as idiopathic. Magnetic resonance imaging (MRI) and cerebral angiography play an important role in the determining the causes of an AIS in children. Medical approaches, including anticoagulation, anti-inflammatories, and antiplatelet therapies, surgical revascularization and endovascular approaches may have a role in the management of AIS in children.


Acute ischemic stroke in children; Arterial dissection; Congenital heart disease; Hyperacute thrombolysis; Moyamoya; Sickle cell disease; Vasculitis

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