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Spine (Phila Pa 1976). 2014 Feb 1;39(3):E191-8. doi: 10.1097/BRS.0000000000000078.

Quality-of-life outcomes with minimally invasive transforaminal lumbar interbody fusion based on long-term analysis of 304 consecutive patients.

Author information

1
From the Department of Neurosurgery, Oakland University William Beaumont School of Medicine, Royal Oak, MI.

Abstract

STUDY DESIGN:

This was a prospective clinical study that took place in an outpatient spine clinic.

OBJECTIVE:

To demonstrate the short-/long-term outcomes from a large cohort of patients undergoing minimally invasive transforaminal lumbar interbody fusion (MITLIF).

SUMMARY OF BACKGROUND DATA:

Long-term prospective outcomes in patients undergoing minimally invasive spinal fusion for debilitating back pain has not been well studied.

METHODS:

Presenting diagnosis was determined from clinical findings and radiographical (radiograph, magnetic resonance image, computed tomographic scan) evaluations preoperatively. Patients were assessed with outcome measures preoperatively, and postoperatively at 2 weeks, 3 months, 6 months, 12 months, 24 months, and annually 2 to 7 years (mean follow-up: 47 mo) final follow-up. The rate of postoperative complications and reoperations at the initial level of MITLIF and adjacent level(s) were followed. Fusion rates were assessed blinded and independently by radiograph.

RESULTS:

Visual analogue scale scores decreased significantly from 7.0 preoperatively to 3.5 at mean 47-month follow-up. Oswestry Disability Index scores declined from 43.1 preoperatively to 28.2 at mean 47-month follow-up. Short-Form 36 mental component scores increased from 43.8 preoperatively to 49.7 at 47-month follow-up. Short-Form 36 physical component scores increased from 30.6 preoperatively to 39.6 at 47-month follow-up (P < 0.05).

CONCLUSION:

This prospectively collected outcomes study shows long-term statistically significant clinical outcomes improvement after MITLIF in patients with clinically symptomatic spondylolisthesis and degenerative disc disease with or without stenosis. MITLIF resulted in a high rate of spinal fusion and very low rate of interbody fusion failure and/or adjacent segment disease requiring reoperation while reducing postoperative complications.

LEVEL OF EVIDENCE:

3.

PMID:
24150437
PMCID:
PMC4047299
DOI:
10.1097/BRS.0000000000000078
[Indexed for MEDLINE]
Free PMC Article
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