Format

Send to

Choose Destination
Cell Host Microbe. 2013 Oct 16;14(4):374-8. doi: 10.1016/j.chom.2013.09.011.

Is RNA interference a physiologically relevant innate antiviral immune response in mammals?

Author information

1
Department of Molecular Genetics & Microbiology and Center for Virology, Duke University Medical Center, Durham, NC 27710, USA. Electronic address: bryan.cullen@duke.edu.

Abstract

While RNA interference (RNAi) functions as an antiviral response in plants, nematodes, and arthropods, a similar antiviral role in mammals has remained controversial. Three recent papers provide evidence that either favors or challenges this hypothesis. Here, we discuss these new findings in the context of previous research.

PMID:
24139396
DOI:
10.1016/j.chom.2013.09.011
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center