The downs and ups of sensory deprivation: evidence for firing rate homeostasis in vivo

Hannah I Bishop; Karen Zito

doi:10.1016/j.neuron.2013.10.011

The downs and ups of sensory deprivation: evidence for firing rate homeostasis in vivo

Neuron. 2013 Oct 16;80(2):247-9. doi: 10.1016/j.neuron.2013.10.011.

Authors

Hannah I Bishop¹, Karen Zito

Affiliation

¹ Department of Neurobiology, Physiology and Behavior, University of California, Davis, Davis, CA 95616, USA.

Abstract

Homeostatic adjustment of neuronal firing rates is considered a vital mechanism to keep neurons operating in their optimal range despite dynamically changing input. Two studies in this issue of Neuron, Hengen et al. (2013) and Keck et al. (2013), provide evidence for firing rate homeostasis in the neocortex of freely behaving rodents.

Publication types

Introductory Journal Article
Comment

MeSH terms

Action Potentials / physiology*
Animals
Female
Homeostasis / physiology*
Male
Neuronal Plasticity / physiology*
Sensory Deprivation / physiology*
Synaptic Transmission / physiology*
Visual Cortex / physiology*

Grants and funding

R01 NS062736/NS/NINDS NIH HHS/United States