Send to

Choose Destination
Clin Med Insights Oncol. 2013 Oct 7;7:257-62. doi: 10.4137/CMO.S12243. eCollection 2013.

Primary monophasic synovial sarcoma of the kidney: a case report and review of literature.

Author information

Department of Medical Oncology, Barretos Cancer Hospital, Barretos, SP, Brazil.


Primary synovial sarcoma (SS) of the kidney is a rare neoplasm and its presenting features are similar to other common renal tumors, making early diagnosis difficult. To date, few cases have been reported in the literature. Primary renal SSs can exist in either a monophasic or a biphasic pattern, the former being more common and tending to have a better prognosis than the biphasic variant. Herein we describe a case of primary renal SS that was diagnosed based on histopathology and immunohistochemistry after radical nephrectomy. Fusion gene product analysis was also done by FISH and RT-PCR. Patient follow-up and literature review are presented, focused on systemic therapy. We highlight that these tumors should be correctly diagnosed as clinical results and specific treatment are distinct from primary epithelial renal cell carcinoma. Adjuvant chemotherapy should be tailored for each patient in the management of disease, although its role still remains unclear.


SYT-SSX fusion protein; chemotherapy; kidney neoplasms; synovial sarcoma

Supplemental Content

Full text links

Icon for Atypon Icon for PubMed Central
Loading ...
Support Center