Format

Send to

Choose Destination
Invest Ophthalmol Vis Sci. 2013 Nov 11;54(12):7378-85. doi: 10.1167/iovs.13-12617.

Intrasession test-retest variability of microperimetry in age-related macular degeneration.

Author information

1
Centre for Eye Research Australia, University of Melbourne, Royal Victorian Eye and Ear Hospital, Victoria, Australia.

Abstract

PURPOSE:

To determine the intrasession test-retest variability of microperimetry in participants with age-related macular degeneration (AMD).

METHODS:

This study consisted of two separate groups of subjects who had not performed microperimetry previously. In group 1, 30 AMD and 14 control participants performed three microperimetry examinations of a selected eye within one session (test 1 and 2, first pair; test 2 and 3, second pair). Follow-up examination at 6 months was available in 20 AMD participants in group 1, who performed two microperimetry examinations. In group 2, 71 AMD participants performed a short practice examination, then two microperimetry examinations of the right eye (test 1 and 2, first pair) and two of the left eye (test 3 and 4, second pair).

RESULTS:

There was a significant improvement in average point-wise sensitivity (PWS) between the first pair of examination in both groups (P < 0.001), but not in the subsequent pair (P ≥ 0.774). This improvement was not observed at the follow-up visit in the subset of AMD participants in group 1 (P = 0.433). The PWS coefficient of repeatability (CoR) for the second pair of examinations was ± 4.12 dB and ± 4.37 dB for AMD participants for group 1 and 2 respectively.

CONCLUSIONS:

A significant increase in sensitivity between the first and second test, but not in the subsequent tests, was found for participants who had not performed microperimetry previously. Intrasession test-retest variability can therefore be minimized by discarding the first examination to avoid the influence of a learning effect.

KEYWORDS:

age-related macular degeneration; microperimetry; repeatability; test–retest; variability

PMID:
24135753
DOI:
10.1167/iovs.13-12617
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Silverchair Information Systems
Loading ...
Support Center