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Cancer Cell. 2013 Oct 14;24(4):401-2. doi: 10.1016/j.ccr.2013.09.016.

NF-κB: a coordinator for epigenetic regulation by MLL.

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1
Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.

Abstract

NF-κB is involved in a variety of biological processes, including cancer development. In this issue of Cancer Cell, Kuo et al. show the essential role for IKK/NF-κB signaling in epigenetic regulation by MLL oncoproteins to maintain leukemia stem cells.

PMID:
24135275
PMCID:
PMC4147035
DOI:
10.1016/j.ccr.2013.09.016
[Indexed for MEDLINE]
Free PMC Article
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