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J Cosmet Laser Ther. 2014 Jun;16(3):132-7. doi: 10.3109/14764172.2013.854119. Epub 2013 Nov 18.

Effects of collagen tripeptide supplement on skin properties: a prospective, randomized, controlled study.

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1
Department of Dermatology, Chung-Ang University College of Medicine , Seoul , South Korea.

Abstract

BACKGROUND:

Experimental and clinical trials have indicated that dietary supplements can have beneficial effects on skin health.

OBJECTIVE:

We investigated to evaluate the effect of daily collagen peptide (CP) supplement on skin properties.

METHODS:

Thirty-two healthy volunteers were randomized to receive either no supplement (Group A), CP 3 g (Group B), CP 3 g, and vitamin C 500 mg (Group C), or vitamin C 500 mg (Group D) daily for 12 weeks. Skin properties evaluated included hydration, transepidermal water loss (TEWL), and elasticity using a corneometer, tewameter, and cutometer, respectively.

RESULTS:

Changes from baseline in the corneometer were statistically significant between Groups A and B (p = 0.011) and Groups A and C (p = 0.004). There were statistically significant differences in cutometer from baseline between Groups A and B (p = 0.005) and Groups A and C (p = 0.015). There was no significant difference from baseline in the corneometer and cutometer between Groups B and C. The greatest changes in TEWL from baseline were seen in Group B, and the second greatest changes were seen in Group C.

CONCLUSIONS:

Daily CP supplementation may improve skin hydration and elasticity, but concomitant intake of low-dose vitamin C did not enhance the effect of CP on skin properties.

KEYWORDS:

collagen tripeptide; skin elasticity; skin hydration

PMID:
24131075
DOI:
10.3109/14764172.2013.854119
[Indexed for MEDLINE]
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