Format

Send to

Choose Destination
Obesity (Silver Spring). 2014 Apr;22(4):1133-41. doi: 10.1002/oby.20620. Epub 2013 Dec 4.

Modifying effect of obesity on the association between sitting and incident diabetes in post-menopausal women.

Author information

1
Department of Aging & Geriatric Research, College of Medicine at the University of Florida, Gainesville, Florida, USA.

Abstract

OBJECTIVE:

To evaluate the association between self-reported daily sitting time and the incidence of type 2 diabetes in a cohort of postmenopausal women.

METHODS:

Women (N=88,829) without diagnosed diabetes reported the number of hours spent sitting over a typical day. Incident cases of diabetes were identified annually by self-reported initiation of using oral medications or insulin for diabetes > 14.4 years follow-up.

RESULTS:

Each hour of sitting time was positively associated with increased risk of diabetes [risk ratio (RR): 1.05; 95% confidence interval (CI): 1.02-1.08]. However, sitting time was only positively associated with incident diabetes in obese women. Obese women reporting sitting 8-11 (RR: 1.08; 95% CI 1.0-1.1), 12-15 (OR: 1.13; 95% CI 1.0-1.2), and ≥16 hours (OR: 1.25; 95% CI 1.0-1.5) hours per day had an increased risk of diabetes compared to women sitting ≤7 hours per day. These associations were adjusted for demographics, health conditions, behaviors (smoking, diet, and alcohol intake), and family history of diabetes. Time performing moderate to vigorous intensity physical activity did not modify these associations.

CONCLUSIONS:

Time spent sitting was independently associated with increased risk of diabetes diagnosis among obese women-a population already at high risk of the disease.

PMID:
24123945
PMCID:
PMC3968183
DOI:
10.1002/oby.20620
[Indexed for MEDLINE]
Free PMC Article

Publication types, MeSH terms, Grant support

Publication types

MeSH terms

Grant support

Supplemental Content

Full text links

Icon for Wiley Icon for PubMed Central
Loading ...
Support Center