Sitosterolemia: platelets on high-sterol diet

Blood. 2013 Oct 10;122(15):2534-5. doi: 10.1182/blood-2013-08-521153.

Abstract

In this issue of Blood, Kanaji et al have identified the cellular mechanisms responsible for the bleeding abnormality and macrothrombocytopenia associated with sitosterolemia.

Publication types

  • Comment

MeSH terms

  • Animals
  • Blood Platelets / physiology*
  • Hemorrhage / blood*
  • Humans
  • Hypercholesterolemia / blood*
  • Intestinal Diseases / blood*
  • Lipid Metabolism, Inborn Errors / blood*
  • Phytosterols / adverse effects*
  • Phytosterols / blood
  • Platelet Activation / physiology*

Substances

  • Phytosterols

Supplementary concepts

  • Sitosterolemia