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J Clin Microbiol. 2013 Nov;51(11):3880-2. doi: 10.1128/JCM.01873-13. Epub 2013 Oct 9.

Consistency of influenza A virus detection test results across respiratory specimen collection methods using real-time reverse transcription-PCR.

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1
Epidemiology and Prevention Branch, Influenza Division, National Center for Immunization and Respiratory Diseases (NCIRD), Centers for Disease Control and Prevention, Atlanta, Georgia, USA.

Abstract

In our prospective cohort study, we compared the performance of nasopharyngeal, oropharyngeal, and nasal swabs for the detection of influenza virus using real-time reverse transcription-PCR assay. Joint consideration of results from oropharyngeal and nasal swabs was as effective as consideration of results from nasopharyngeal swabs alone, as measured by sensitivity and noninferiority analysis.

PMID:
24108606
PMCID:
PMC3889789
DOI:
10.1128/JCM.01873-13
[Indexed for MEDLINE]
Free PMC Article
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