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Acta Otolaryngol. 2014 Jan;134(1):26-33. doi: 10.3109/00016489.2013.835866. Epub 2013 Oct 9.

The temporal bone microdissection of miniature pigs as a useful large animal model for otologic research.

Author information

1
Department of Neurosurgery Division 9 and Otolaryngeal-Head Neck Surgery, Beijing Tiantan Hospital, Capital University of Medical Science , Beijing , China.

Abstract

CONCLUSION:

Compared with traditional animal models, the miniature pig may be a better model for biomedical research because its morphology has many similarities with that of humans.

OBJECTIVE:

To investigate the suitability of the miniature pig as an animal model for otological research as regards morphology.

METHODS:

Microdissection of the temporal bone of 10 miniature pigs was performed and recorded on photographs.

RESULTS:

The morphology and measurements of the external, middle, and inner ear, and the lateral recess of the miniature pigs were completed by microdissection. The temporal bone structures, including the external, middle, inner ear, and the lateral recess, were similar in the miniature pig and humans.

PMID:
24102225
DOI:
10.3109/00016489.2013.835866
[Indexed for MEDLINE]
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