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Pediatr Clin North Am. 2013 Oct;60(5):1063-82. doi: 10.1016/j.pcl.2013.06.011. Epub 2013 Jul 30.

Skin and soft tissue infections.

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Section of Pediatric Emergency Medicine, Department of Pediatrics, Children's Hospital Colorado, University of Colorado School of Medicine, 13123 East 16th Avenue, Box B251, Aurora, CO 80045, USA. Electronic address:


The approach to common skin and soft tissue infections (SSTIs) was previously well understood. However, the recent emergence of community-associated methicillin resistant Staphyloccocus aureus as a common pathogen has changed the epidemiology of these infections and has led clinicians to alter their practice and treatment of SSTI. This article discusses the present epidemiology of SSTI and community-acquired methicillin-resistant Staphylococcus aureus, evidence-based approach to incision and drainage, the utility of adjuvant antibiotic therapy after abscess drainage, and current antimicrobial approach to cellulitis and nondrained SSTIs. Methods to reduce transmission and recurrence of SSTI through decolonization strategies are also discussed.


Cellulitis; Cutaneous abscess; Skin infection; Staphylococcus aureus

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