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J Biomed Res. 2013 Sep;27(5):357-65. doi: 10.7555/JBR.27.20120128. Epub 2013 Mar 10.

Goal-directed therapy in intraoperative fluid and hemodynamic management.

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Department of Anesthesiology and Pain Medicine, University of California Davis Health System, Sacramento, CA 95817, USA.


Intraoperative fluid management is pivotal to the outcome and success of surgery, especially in high-risk procedures. Empirical formula and invasive static monitoring have been traditionally used to guide intraoperative fluid management and assess volume status. With the awareness of the potential complications of invasive procedures and the poor reliability of these methods as indicators of volume status, we present a case scenario of a patient who underwent major abdominal surgery as an example to discuss how the use of minimally invasive dynamic monitoring may guide intraoperative fluid therapy.


fluid; goal-directed therapy; hemodynamic; high-risk surgery; monitoring

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