Asbestos-induced mesothelioma: is fiber biopersistence really a critical factor?

Elliott Kagan

doi:10.1016/j.ajpath.2013.09.005

Asbestos-induced mesothelioma: is fiber biopersistence really a critical factor?

Am J Pathol. 2013 Nov;183(5):1378-1381. doi: 10.1016/j.ajpath.2013.09.005. Epub 2013 Sep 29.

Author

Elliott Kagan¹

Affiliation

¹ Department of Pathology, Uniformed Services University of the Health Sciences, Bethesda, Maryland. Electronic address: elliott.kagan@usuhs.edu.

PMID: 24084028
DOI: 10.1016/j.ajpath.2013.09.005

Abstract

This Commentary highlights the research by Qi et al detailing the similarities and differences between crocidolite and chrysotile asbestos in terms of their transcriptional effects and transforming actions in human mesothelial cells.

Published by Elsevier Inc.

Publication types

Comment

MeSH terms

Animals
Asbestos, Serpentine / toxicity*
Cell Transformation, Neoplastic / metabolism*
Cell Transformation, Neoplastic / pathology*
Epithelium / pathology*
HMGB1 Protein / metabolism*
Humans
Signal Transduction / drug effects*
Tumor Necrosis Factor-alpha / metabolism*

Substances

Asbestos, Serpentine
HMGB1 Protein
Tumor Necrosis Factor-alpha