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BMC Surg. 2013 Oct 1;13:44. doi: 10.1186/1471-2482-13-44.

Laparoscopic liver resection as a safe and efficacious alternative to open resection for colorectal liver metastasis: a meta-analysis.

Author information

1
Department of Hepatobiliary & Pancreatovascular Surgery, Oncologic Center of Xiamen, First affiliated Hospital of Xiamen University, Xiamen, China. zhouymsxy@sina.cn.

Abstract

BACKGROUND:

The safety and efficacy of laparoscopic liver resection (LLR) for colorectal liver metastasis (CLM) remain to be established. A meta-analysis was undertaken to compare LLR and open liver resection (OLR) for CLM with respect to surgical and oncologic outcomes.

METHODS:

An electronic search was performed to retrieve all relevant articles published in the English language by the end of March 2013. Data were analyzed using Review Manager version 5.0.

RESULTS:

A total of 8 nonrandomized controlled studies with 695 subjects were analyzsed. Intra-operative blood loss, the proportion of patients requiring blood transfusion, morbidity and the length of hospital stay were all significantly reduced after LLR. Postoperative recurrence, 5-year overall and disease-free survivals were comparable between two groups.

CONCLUSIONS:

LLR for CLM is safe and efficacious. It improves surgical outcomes and uncompromises oncologic outcomes as compared with OLR.

PMID:
24083369
PMCID:
PMC3849970
DOI:
10.1186/1471-2482-13-44
[Indexed for MEDLINE]
Free PMC Article
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