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Indian J Dermatol. 2013 Sep;58(5):408. doi: 10.4103/0019-5154.117341.

A rare case of familial reactive perforating collagenosis.

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Department of Dermatology, Command Hospital, Pune, India.


A 4 year old boy presented with history of itchy raised lesions on body of 2 years duration. Though parental consanguinity was not present, his elder brother had similar complaints. Dermatological examination revealed multiple hyperpigmented papules with a central keratotic plug distributed mainly over face and extensors of upper and lower extremities. Koebnerisation was present. Skin biopsy revealed perforating collagen bundles in the upper dermis and epidermis which was confirmed by Van Gieson staining. Patient was being treated with topical retinoids and intralesional corticosteroids with minimal relief.


Collagen; perforating disorders; reactive perforating collagenosis; retinoids

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