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Database (Oxford). 2013 Sep 29;2013:bat068. doi: 10.1093/database/bat068. Print 2013.

yApoptosis: yeast apoptosis database.

Author information

1
Department of Chemical and Biological Engineering, Chalmers University of Technology, Kemivägen 10, 41296, Gothenburg, Sweden, Department of Mathematics, Chalmers University of Technology, Chalmers tvärgata 3, 41296, Gothenburg, Sweden, Department of Mathematics, University of Gothenburg, Chalmers tvärgata 3, 41296, Gothenburg, Sweden and Fine Chemicals and Biocatalysis Research, BASF SE, GVF/D - A030, 67056 Ludwigshafen, Germany.

Abstract

In the past few years, programmed cell death (PCD) has become a popular research area due to its fundamental aspects and its links to human diseases. Yeast has been used as a model for studying PCD, since the discovery of morphological markers of apoptotic cell death in yeast in 1997. Increasing knowledge in identification of components and molecular pathways created a need for organization of information. To meet the demands from the research community, we have developed a curated yeast apoptosis database, yApoptosis. The database structurally collects an extensively curated set of apoptosis, PCD and related genes, their genomic information, supporting literature and relevant external links. A web interface including necessary functions is provided to access and download the data. In addition, we included several networks where the apoptosis genes or proteins are involved, and present them graphically and interactively to facilitate rapid visualization. We also promote continuous inputs and curation by experts. yApoptosis is a highly specific resource for sharing information online, which supports researches and studies in the field of yeast apoptosis and cell death. DATABASE URL: http://www.ycelldeath.com/yapoptosis/.

PMID:
24082050
PMCID:
PMC3786231
DOI:
10.1093/database/bat068
[Indexed for MEDLINE]
Free PMC Article

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