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Colloids Surf B Biointerfaces. 2014 Jan 1;113:146-51. doi: 10.1016/j.colsurfb.2013.08.038. Epub 2013 Sep 5.

Alginate/cashew gum nanoparticles for essential oil encapsulation.

Author information

1
Department of Analytical and Physical Chemistry, Federal University of Ceará, UFC, Fortaleza-CE, Brazil.
2
Department of Analytical and Physical Chemistry, Federal University of Ceará, UFC, Fortaleza-CE, Brazil. Electronic address: hpaula@ufc.br.
3
Department of Organic and Inorganic Chemistry, Federal University of Ceará, UFC, Fortaleza-CE, Brazil.

Abstract

Alginate/cashew gum nanoparticles were prepared via spray-drying, aiming at the development of a biopolymer blend for encapsulation of an essential oil. Nanoparticles were characterized regarding to their hydrodynamic volume, surface charge, Lippia sidoides essential oil content and release profile, in addition to being analyzed by infrared spectroscopy (FT-IR), thermal analysis (TGA/DSC) and X-ray diffractometry. Nanoparticles in solution were found to have averaged sizes in the range 223-399 nm, and zeta potential values ranging from -30 to -36 mV. Encapsulated oil levels varied from 1.9 to 4.4% with an encapsulation efficiency of up to 55%. The in vitro release profile showed that between 45 and 95% of oil was released within 30-50h. Kinetic studies revealed that release pattern follow a Korsmeyer-Peppas mechanism.

KEYWORDS:

Alginate; Cashew gum; Encapsulation; Lippia sidoides; Nanoparticles

PMID:
24077112
DOI:
10.1016/j.colsurfb.2013.08.038
[Indexed for MEDLINE]

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