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Patient Educ Couns. 2013 Dec;93(3):413-9. doi: 10.1016/j.pec.2013.08.009. Epub 2013 Aug 19.

Implementation and outcomes of telephone disclosure of clinical BRCA1/2 test results.

Author information

1
Department of Medicine, Division of Hematology-Oncology, The University of Chicago, Chicago, USA; Center for Clinical Cancer Genetics and Global Health, The University of Chicago, Chicago, USA.

Abstract

OBJECTIVES:

With an increasing demand for genetic services, effective and efficient delivery models for genetic testing are needed.

METHODS:

In this prospective single-arm communication study, participants received clinical BRCA1/2 results by telephone with a genetic counselor and completed surveys at baseline, after telephone disclosure (TD) and after in-person clinical follow-up.

RESULTS:

Sixty percent of women agreed to participate; 73% of decliners preferred in-person communication. Anxiety decreased from baseline to post-TD (p=0.03) and satisfaction increased (p<0.01). Knowledge did not change significantly from baseline to post-TD, but was higher post-clinical follow-up (p=0.04). Cancer patients had greater declines in state anxiety and African-American participants reported less increase in satisfaction. 28% of participants did not return for in-person clinical follow-up, particularly those with less formal education, and higher post-disclosure anxiety and depression (p<0.01).

CONCLUSIONS:

Telephone disclosure of BRCA1/2 test results may not be associated with negative cognitive and affective responses among willing patients, although some subgroups may experience less favorable responses. Some patients do not return for in-person clinical follow-up and longitudinal outcomes are unknown.

PRACTICE IMPLICATIONS:

Further evaluation of longitudinal outcomes of telephone disclosure and differences among subgroups can inform how to best incorporate telephone communication into delivery of genetic services.

KEYWORDS:

Cancer risk assessment; Cancer susceptibility; Communication; Genetic testing

PMID:
24075727
PMCID:
PMC4199583
DOI:
10.1016/j.pec.2013.08.009
[Indexed for MEDLINE]
Free PMC Article
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