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Mol Cell. 2013 Sep 26;51(6):703-4. doi: 10.1016/j.molcel.2013.09.011.

TERRA -a calling card for telomerase.

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1
Howard Hughes Medical Institute and Stowers Institute for Medical Research, Kansas City, MO 64110, USA.

Abstract

Transcription of telomeric DNA has long been thought to inhibit telomerase. Using live cell imaging, in this issue, Cusanelli et al. (2013) now reveal a different scenario: telomeric RNA is preferentially generated at short telomeres and delivers telomerase to the chromosome end from which the transcript originated.

PMID:
24074950
DOI:
10.1016/j.molcel.2013.09.011
[Indexed for MEDLINE]
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