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Cell. 2013 Sep 26;155(1):19-20. doi: 10.1016/j.cell.2013.09.010.

Cerebral organoids in a dish: progress and prospects.

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1
Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, 35 Medical Center Way, San Francisco, CA 94143, USA; University of California, San Francisco, San Francisco, CA 94143, USA.

Abstract

A three-dimensional culture of cortical tissues derived from pluripotent stem cells offers an opportunity to model human brain development and disorders. In a recent issue of Nature, Lancaster et al. describe a new method for generating cerebral organoids in a dish and use it to model microcephaly.

PMID:
24074857
PMCID:
PMC5127703
DOI:
10.1016/j.cell.2013.09.010
[Indexed for MEDLINE]
Free PMC Article
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