Format

Send to

Choose Destination
Front Cell Infect Microbiol. 2013 Sep 18;3:53. doi: 10.3389/fcimb.2013.00053. eCollection 2013.

Through the dark continent: African trypanosome development in the tsetse fly.

Author information

1
Trypanosome Cell Biology Unit, Institut Pasteur and CNRS URA 2581, Paris, France. rotureau@pasteur.fr

Abstract

African trypanosomes are unicellular flagellated parasites causing trypanosomiases in Africa, a group of severe diseases also known as sleeping sickness in human and nagana in cattle. These parasites are almost exclusively transmitted by the bite of the tsetse fly. In this review, we describe and compare the three developmental programs of the main trypanosome species impacting human and animal health, with focus on the most recent observations. From here, some reflections are made on research issues concerning trypanosome developmental biology in the tsetse fly that are to be addressed in the future.

KEYWORDS:

African trypanosomes; development; parasite cycle; tsetse fly; vector

PMID:
24066283
PMCID:
PMC3776139
DOI:
10.3389/fcimb.2013.00053
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for PubMed Central
Loading ...
Support Center