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J Child Neurol. 2014 Jul;29(7):943-6. doi: 10.1177/0883073813501873. Epub 2013 Sep 23.

Functional relapses in pediatric multiple sclerosis.

Author information

1
Partners Pediatric Multiple Sclerosis Center, Department of Child Neurology Massachusetts General Hospital, Boston, MA, USA.
2
Partners Pediatric Multiple Sclerosis Center, Department of Child Neurology Massachusetts General Hospital, Boston, MA, USA Department of Child Psychiatry, Massachusetts General Hospital, Boston, MA, USA.
3
Department of Child Psychiatry, Massachusetts General Hospital, Boston, MA, USA.
4
Partners Pediatric Multiple Sclerosis Center, Department of Child Neurology Massachusetts General Hospital, Boston, MA, USA tchitnis@partners.org.

Abstract

Multiple sclerosis in children is characterized by more frequent relapses than in adult patients. Diagnosing and treating youth with multiple sclerosis present a number of challenges including differentiating organic relapses from functional symptoms. However, there is no literature describing coexistence of functionality in pediatric multiple sclerosis. Here, we report 2 cases in which inconsistency between clinical history, physical examination, imaging, and atypical disease progression led to suspicion of functional relapses. The purpose of this study is to raise awareness of functional relapses, as prompt recognition can prevent overtreatment and iatrogenic risks in children and adolescents with multiple sclerosis. Underlying psychiatric issues also need to be addressed.

KEYWORDS:

Pediatric multiple sclerosis; children and adolescents; functional relapses

PMID:
24065582
DOI:
10.1177/0883073813501873
[Indexed for MEDLINE]

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