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Int J Mol Sci. 2013 Sep 13;14(9):18925-58. doi: 10.3390/ijms140918925.

The clinical utilization of circulating cell free DNA (CCFDNA) in blood of cancer patients.

Author information

1
Division of Cancer Research and Training, Department of Internal Medicine, Charles Drew University of Medicine and Science, 1720 East 120th Street, Los Angeles, CA 90059, USA. elshimali@gmail.com.

Abstract

Qualitative and quantitative testing of circulating cell free DNA (CCFDNA) can be applied for the management of malignant and benign neoplasms. Detecting circulating DNA in cancer patients may help develop a DNA profile for early stage diagnosis in malignancies. The technical issues of obtaining, using, and analyzing CCFDNA from blood will be discussed.

PMID:
24065096
PMCID:
PMC3794814
DOI:
10.3390/ijms140918925
[Indexed for MEDLINE]
Free PMC Article

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