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J Immunoassay Immunochem. 2014;35(1):101-9. doi: 10.1080/15321819.2013.792834.

Investigation of the relation between anaerobic bacteria genus clostridium and late-onset autism etiology in children.

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1
a Department of Microbiology , Konya Education and Research Hospital , Konya , Trukey.

Abstract

The aim of this study was to investigate the relation between the etiology of late-onset childhood autism and anaerobic bacteria. Thirty children diagnosed with autistic disorder and control group have been included in the study. 3-(3-hydroxy phenyl)-3-hydroxypropionic acid (HPHPA) excretion rates which is a metabolic product of the genus Clostridium, were measured via mass spectrometry-gas chromatography (MS-GC) method from urine samples. When the assayed average HPHPA values compared with each group, a statistically significant difference was found (p < 0.05). Data obtained from this study support the existence of a significant correlation between autism etiology and anaerobic bacteria.

PMID:
24063620
DOI:
10.1080/15321819.2013.792834
[Indexed for MEDLINE]
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