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Am J Trop Med Hyg. 2013 Nov;89(5):840-849. doi: 10.4269/ajtmh.13-0028. Epub 2013 Sep 23.

Mapping malaria transmission intensity in Malawi, 2000-2010.

Abstract

Substantial development assistance has been directed towards reducing the high malaria burden in Malawi over the past decade. We assessed changes in transmission over this period of malaria control scale-up by compiling community Plasmodium falciparum rate (PfPR) data during 2000-2011 and used model-based geostatistical methods to predict mean PfPR2-10 in 2000, 2005, and 2010. In addition, we calculated population-adjusted prevalences and populations at risk by district to inform malaria control program priority setting. The national population-adjusted PfPR2-10 was 37% in 2010, and we found no evidence of change over this period of scale-up. The entire population of Malawi is under meso-endemic transmission risk, with those in districts along the shore of Lake Malawi and Shire River Valley under highest risk. The lack of change in prevalence confirms modeling predictions that when compared with lower transmission, prevalence reductions in high transmission settings require greater investment and longer time scales.

PMID:
24062477
PMCID:
PMC3820324
DOI:
10.4269/ajtmh.13-0028
[Indexed for MEDLINE]
Free PMC Article

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