Format

Send to

Choose Destination
Am J Surg. 2014 Jan;207(1):53-9. doi: 10.1016/j.amjsurg.2013.04.006. Epub 2013 Sep 17.

Incidence, risk factors, and outcomes of perioperative acute kidney injury in noncardiac and nonvascular surgery.

Author information

1
Medipol University, Faculty of Medicine, Department of Cardiology, Istanbul, Turkey. Electronic address: murbit2@yahoo.com.
2
Department of Family Medicine, Haydarpaşa Numune Education and Research Hospital, Istanbul, Turkey.
3
Department of Cardiology, Dr. Siyami Ersek Cardiovascular and Thoracic Surgery Research and Training Hospital, Istanbul, Turkey.
4
Department of Cardiology, Bagcılar Education and Research Hospital, Istanbul, Turkey.
5
Department of Internal Medicine, Haydarpaşa Numune Education and Research Hospital, Istanbul, Turkey.
6
Department of Cardiology, Van Erciş State Hospital, Van, Turkey.
7
Department of Nephrology, Haydarpaşa Numune Education and Research Hospital, Istanbul, Turkey.

Abstract

BACKGROUND:

The aim of this study was to determine the incidence rate, identify the risk factors, and describe the clinical outcome of perioperative acute kidney injury (AKI) in patients undergoing noncardiac, nonvascular surgery (NCS).

METHODS:

A total of 1,200 adult consecutive patients undergoing NCS were prospectively evaluated. Patients with pre-existing renal dysfunction were excluded. The primary outcome of this study was perioperative AKI defined by the RIFLE (risk, injury, failure, loss of function, and end-stage kidney disease) criteria.

RESULTS:

Eighty-one patients (6.7%) met the AKI criteria. Multivariate analysis identified age, diabetes, revised cardiac risk index, and American Society of Anesthesiologists physical status as independent predictors of AKI. Patients with AKI had more cardiovascular (33.3% vs 11.3%, P < .001) complications and a higher in-hospital mortality rate (6.1% vs 0.9%, P = .003) compared with patients without AKI.

CONCLUSIONS:

Several preoperative predictors are found to be associated with AKI after NCS. Perioperative AKI is an independent risk factor for outcome after NCS.

KEYWORDS:

Noncardiac surgery; Outcome; Perioperative acute kidney injury

PMID:
24050540
DOI:
10.1016/j.amjsurg.2013.04.006
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center