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Curr Osteoporos Rep. 2013 Sep;11(3):179-87. doi: 10.1007/s11914-013-0167-y.

Atypical femoral fractures: a review of the literature.

Author information

1
Metabolic Bone Disease, Hospital for Special Surgery, 535 East 70th Street, New York, NY, 10021, USA, desaip@hss.edu.

Abstract

Bisphosphonates are the most commonly used drugs worldwide for treating osteoporosis. Atypical femoral fractures most commonly are associated with prolonged bisphosphonate use. They also may occur with denosumab use or in patients without a history of using these drugs. In this article, we provide a comprehensive review of the mechanism of action of bisphosphonate and the definition, incidence, epidemiology, pathogenesis, diagnosis, management, and prevention of atypical femoral fractures.

PMID:
24048722
DOI:
10.1007/s11914-013-0167-y
[Indexed for MEDLINE]

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