Format

Send to

Choose Destination
Curr Cardiol Rep. 2013 Oct;15(10):399. doi: 10.1007/s11886-013-0399-6.

Mendelian forms of structural cardiovascular disease.

Author information

1
Cardiovascular Division, Brigham and Women's Hospital, Boston, MA, 02115, USA. camacrae@bics.bwh.harvard.edu

Abstract

Clinical and molecular genetics are inextricably linked. In the last two decades genetic studies have revealed the causes of several forms of structural heart disease. Recent work is extending the insights from inherited arrhythmias and cardiomyopathies to other forms of heart disease. In this review we outline the current state of the art for the genetics of adult structural heart disease, in particular the cardiomyopathies, valvular heart disease and aortic disease. The general approaches are described with a focus on clinical relevance, while potential areas for imminent innovation in diagnosis and therapeutics are highlighted.

PMID:
24046092
PMCID:
PMC3884814
DOI:
10.1007/s11886-013-0399-6
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Springer Icon for PubMed Central
Loading ...
Support Center