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Cardiovasc Clin. 1990;20(2):3-19.

The history of heart and heart-lung transplantation.


The current success of heart and heart-lung transplantation is grounded in a long progression of experimental and clinical advances. Beginning with an isolated heart transplant performed as a technical exercise in 1905, slowly accumulated experimental efforts yielded solutions to problems involving technique, recipient and graft protection, post-transplant function and immunology, and provided a foundation for subsequent clinical applications. Clinical studies augmented these observations and addressed legal and logistic issues involved in human transplantation.

[Indexed for MEDLINE]

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