Format

Send to

Choose Destination
See comment in PubMed Commons below
Cardiol Young. 2014 Oct;24(5):822-30. doi: 10.1017/S104795111300111X. Epub 2013 Sep 18.

The value of stress perfusion cardiovascular magnetic resonance imaging for patients referred from the adult congenital heart disease clinic: 5-year experience at the Toronto General Hospital.

Author information

1
1Department of Medical Imaging,Peter Munk Cardiac Centre,Toronto General Hospital,University of Toronto,Ontario,Canada.
2
2Radiology Department,Hospital de ClĂ­nicas de Porto Alegre,Porto Alegre,Rio Grande do Sul,Brazil.
3
3Division of Cardiology,Peter Munk Cardiac Centre,Toronto General Hospital,University of Toronto,Ontario,Canada.
4
4Department of Medical Imaging,Sunnybrook Health Sciences Centre,Toronto,Ontario,Canada.

Abstract

BACKGROUND:

Vasodilator stress perfusion cardiovascular magnetic resonance imaging is a clinically useful tool for detection of clinically significant myocardial ischaemia in adults. We report our 5-year retrospective experience with perfusion cardiovascular magnetic resonance in a large, quarternary adult congenital heart disease centre.

METHODS:

We reviewed all cases of perfusion cardiovascular magnetic resonance in patients referred from the adult congenital heart disease service. Dipyridamole stress perfusion cardiovascular magnetic resonance was undertaken on commercially available 1.5 and 3 T cardiovascular magnetic resonance scanners. Late gadolinium enhancement imaging was performed 8-10 minutes after completion of the rest perfusion sequence. Navigator whole-heart coronary magnetic resonance angiography was also performed where feasible. RESULTS of stress cardiovascular magnetic resonance were correlated with complementary imaging studies, surgery, and clinical outcomes.

RESULTS:

Over 5 years, we performed 34 stress perfusion cardiovascular magnetic resonance examinations (11 positive). In all, 84% of patients had further investigations for ischaemia in addition to cardiovascular magnetic resonance. Within a subgroup of 19 patients who had definitive alternative assessment of their coronary arteries, stress perfusion cardiovascular magnetic resonance demonstrated a sensitivity of 82% and specificity of 100%. Of the 34 studies, two were false negatives, in which the aetiology of ischaemia was extrinsic arterial compression rather than intrinsic coronary luminal narrowing. Coronary abnormalities were identified in 71% of cases who had coronary magnetic resonance angiography.

CONCLUSION:

Stress perfusion cardiovascular magnetic resonance is a useful and accurate tool for investigation of myocardial ischaemia in an adult congenital heart disease population with suspected non-atherosclerotic coronary abnormalities.

PMID:
24044501
DOI:
10.1017/S104795111300111X
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Cambridge University Press
    Loading ...
    Support Center