Format

Send to

Choose Destination
See comment in PubMed Commons below
Mitochondrial DNA. 2015 Apr;26(2):284-6. doi: 10.3109/19401736.2013.825777. Epub 2013 Sep 16.

The whole mitochondrial genome of the Cynomolgus macaque (Macaca fascicularis).

Author information

1
State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming , Yunnan Province , China .

Abstract

Macaca fascicularis, known as the long-tailed macaque, is widely distributed in southern of East Asia and Southeast Asia. It was one of the most commonly used non-human primates in biomedical research. Thus, to illustrate the maternal phylogenetic status of M. fascicularis in primates based on the whole mitochondrial DNA (mtDNA) genome and determine a reference sequence for future population genetic studies by taking mtDNA as molecular marker, in this study, the high quality whole mtDNA genome of M. fascicularis was amplified and sequenced. Our data showed that the whole mtDNA genome of M. fascicularis includes 16,571 base pairs (bps). Further phylogenetic analyses of M. fascicularis were performed by incorporating the 83 available whole mtDNA genomes belonging to 77 primate species with Tupaia belangeri as out-group. Our result supported that M. fascicularis belongs to Macaca. Cercopithecinae. Cercopithecidae. Anthropoidea. Primates, which has the closest genetic affinity with Macaca mulatta. In addition, the ancestral divergence between the tarsier and other primate species was supported with evidence from the whole mtDNA genomes.

KEYWORDS:

Macaca fascicularis; phylogenetic analysis; whole mitochondrial DNA genome

PMID:
24041448
DOI:
10.3109/19401736.2013.825777
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Taylor & Francis
    Loading ...
    Support Center