Use of danazol in conservative surgery

J Reprod Med. 1990 Jan;35(1 Suppl):82-4; discussion 84-6.

Abstract

Any type of injury, inflammation or noninfectious condition can cause an adhesion. Among noninfectious conditions that cause adhesions, endometriosis is the most common. a six-month preoperative regimen of Danocrine (danazol) resulted in a reduction in pelvic vascularity and inflammation, theoretically reducing the risk of postoperative adhesions. The preoperative use of danazol also makes laparoscopic surgery possible for more patients.

Publication types

  • Review

MeSH terms

  • Combined Modality Therapy
  • Danazol / therapeutic use*
  • Endometriosis / drug therapy*
  • Endometriosis / surgery*
  • Female
  • Humans
  • Peritoneal Diseases / prevention & control
  • Postoperative Complications / prevention & control
  • Pregnadienes / therapeutic use*
  • Premedication*
  • Tissue Adhesions / prevention & control

Substances

  • Pregnadienes
  • Danazol