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Cell. 2013 Sep 12;154(6):1190-3. doi: 10.1016/j.cell.2013.08.028.

Long noncoding RNAs usher in a new era in the biology of enhancers.

Author information

1
Max Planck Institute for Molecular Genetics, 14195 Berlin, Germany. Electronic address: oerom@molgen.mpg.de.

Abstract

Enhancer-associated long noncoding RNAs act over long distances and across chromosomes to activate transcription at distal promoters. Here, we address the latest advances made toward understanding the role of long noncoding RNA expression and the involvement of these RNAs in enhancer function through association with protein factors and modulation of chromatin structure.

PMID:
24034243
PMCID:
PMC4108076
DOI:
10.1016/j.cell.2013.08.028
[Indexed for MEDLINE]
Free PMC Article

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