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Saudi J Kidney Dis Transpl. 2013 Sep;24(5):969-75.

Combined liver and kidney transplantation in primary hyperoxaluria: a report of three cases and review of the literature.

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Department of Nephrology, Hamad Al Essa, Organ Transplant Center, Kuwait.


Primary hyperoxaluria type-1 (PH-1) is a rare autosomal recessive metabolic disorder leading to excessive oxalate production, deposition of calcium oxalate crystals in the kidney, nephrocalcinosis, progressive renal failure and systemic deposition of oxalate (oxalosis). Combined liver and kidney transplantation (LKT), which has been accepted as the treatment of choice for PH-1, has considerably improved patient and graft survival. Herein, we report our experience of three children with PH-1 who underwent combined LKT, with a review of the literature.

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