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Transfus Apher Sci. 2013 Oct;49(2):318-22. doi: 10.1016/j.transci.2013.08.005. Epub 2013 Aug 26.

Six-year pilot study on nucleic acid testing for blood donations in China.

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1
Shenzhen Blood Centre, Shenzhen, China.

Abstract

A six-year pilot study on nucleic acid testing for HBV, HCV and HIV-1 has been undertaken on sero-negative plasmas in mini-pool and individual donation testing at Shenzhen Blood Center. Of 307,740 sero-negative blood samples, 95 of 102 HBV DNA yields were confirmed positive, 80/95 (84.2%) were classified as occult HBV infection (OBI) and 15 (15.8%) as window period cases. Amongst OBIs, 45% carried anti-HBc only, 41.3% anti-HBc and anti-HBs and 13.7% anti-HBs only. HBV DNA yield was 1:3239. One HCV WP and one HIV-1 infected donations were detected. High residual risk was found in current blood donations screening in China.

KEYWORDS:

Blood donors; Blood safety; Nucleic acid testing; Viruses

PMID:
24007868
DOI:
10.1016/j.transci.2013.08.005
[Indexed for MEDLINE]
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