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Cold Spring Harb Perspect Med. 2013 Sep 1;3(9):a014332. doi: 10.1101/cshperspect.a014332.

Control of vertebrate development by MYC.

Author information

1
Shriners Hospitals for Children Portland, Portland, Oregon 97239.

Abstract

The study of MYC has led to pivotal discoveries in cancer biology, induced pluripotency, and transcriptional regulation. In this review, continuing advances in our understanding of the function of MYC as a transcription factor and how its transcriptional activity controls normal vertebrate development and contributes to developmental disorders is discussed.

PMID:
24003246
PMCID:
PMC3753724
DOI:
10.1101/cshperspect.a014332
[Indexed for MEDLINE]
Free PMC Article

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