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Mult Scler. 2014 Apr;20(5):610-6. doi: 10.1177/1352458513503598. Epub 2013 Sep 2.

The impact of sexual dysfunction on health-related quality of life in people with multiple sclerosis.

Author information

1
Ferkauf Graduate School of Psychology, Yeshiva University, USA.

Abstract

BACKGROUND:

Sexual dysfunction is a prevalent symptom in multiple sclerosis (MS) that may affect patients' health-related quality of life (HrQoL).

OBJECTIVE:

The objective of this paper is to examine the impact of sexual dysfunction on HrQoL in a large national sample using The Multiple Sclerosis Intimacy and Sexuality Questionnaire-19 (MSISQ-19).

METHODS:

Participants were recruited from a large MS registry, the North American Research Committee on Multiple Sclerosis (NARCOMS) Registry. Participants self-reported demographic information and completed the Patient Determined Disease Steps (PDDS), MSISQ-19, and the Short Form-12 (SF-12).

RESULTS:

The study population included 6183 persons (mean age: 50.6, SD = 9.6; 74.7% female, 42.3% currently employed). Using multivariate hierarchical regression analyses, all variables excluding gender predicted both the physical component summary (PCS-12) and the mental component summary (MCS-12) of the SF-12. Scores on the MSISQ-19 uniquely accounted for 3% of the variance in PCS-12 scores while disability level, as measured by PDDS, accounted for 31% of the variance. Conversely, MSISQ-19 scores uniquely accounted for 13% of the variance in MCS-12 scores, whereas disability level accounted for less than 1% of the variance.

CONCLUSION:

In patients with MS, sexual dysfunction has a much larger detrimental impact on the mental health aspects of HrQoL than severity of physical disability.

KEYWORDS:

Multiple sclerosis; quality of life

PMID:
23999609
DOI:
10.1177/1352458513503598
[Indexed for MEDLINE]
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