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Cell. 2013 Aug 29;154(5):957-959. doi: 10.1016/j.cell.2013.08.020.

Breast cancer bone metastases: it's all about the neighborhood.

Author information

1
Department of Medicine, Division of Endocrinology, Indiana University, Indianapolis, IN 46202, USA. Electronic address: tguise@iu.edu.

Abstract

In order to establish themselves in distal sites, metastatic cancer cells need to acquire organ-specific traits. Zhang et al. provide evidence in breast cancer that a tumor cell's acquisition of properties for successful bone metastasis is influenced by signals from the stroma of the primary tumor.

PMID:
23993088
DOI:
10.1016/j.cell.2013.08.020
[Indexed for MEDLINE]
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