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Int J Antimicrob Agents. 2013 Nov;42(5):450-5. doi: 10.1016/j.ijantimicag.2013.07.005. Epub 2013 Aug 11.

Ceftaroline for meticillin-resistant Staphylococcus aureus bacteraemia: case series and review of the literature.

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1
Wright State University Boonshoft School of Medicine, Miami Valley Hospital, 128 East Apple Street, Weber CHE 2nd Floor, Dayton, OH 45409, USA. Electronic address: haralampie1909@gmail.com.

Abstract

Data regarding ceftaroline use for meticillin-resistant Staphylococcus aureus bacteraemia (MRSAB) are lacking. Here we review the outcomes of 31 patients with MRSAB treated with ceftaroline, including 9 patients with endocarditis. Clinical success was observed in 23 patients (74.2%). Adverse events associated with prolonged therapy were rare and included eosinophilic pneumonia, rash and diarrhoea. We conclude that ceftaroline can be used for MRSAB.

KEYWORDS:

Bacteraemia; Ceftaroline; Endocarditis; MRSA; Meticillin-resistant Staphylococcus aureus

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