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Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2013 Aug;35(4):427-31. doi: 10.3881/j.issn.1000-503X.2013.04.013.

[Relationship between maternal milk and serum thyroid hormones in patients with thyroid related diseases].

[Article in Chinese]

Author information

1
Department of Endocrinology, PUMC Hospital, Beijing, China.

Abstract

OBJECTIVE:

To explore the relationship between maternal milk and serum thyroid hormones in patients with thyroid-related diseases.

METHODS:

Serum and breast milk samples were collected from 56 breastfeeding mothers. Milk and serum free triiodothyronine (FT3), free thyroxine (FT4), triiodothyronine(T3), thyroxine (T4), and thyrotrophin (TSH) were determined, and T3/T4 was calculated. Using the serum thyroid hormones as the independent variables and milk thyroid hormones as the dependent variables, we performed linear regression analysis.

RESULTS:

The milk FT3, FT4, T3, T4, TSH, and T3/T4 were (2.30 ± 0.82) pg/ml ,(0.45 ± 0.26) ng/dl, (0.35 ± 0.20) ng/ml, (2.96 ± 1.55) Μg/dl, (0.12 ± 0.08) ΜU/ml, and 0.12 ± 0.04, respectively. Milk FT3 (r = 0.778, P = 0.000), T3 (r = 0.603, P = 0.000), T4 (r = 0.485, P = 0.004), and TSH (r = 0.605, P = 0.000) concentrations were positively correlated with those in serum.

CONCLUSION:

Thyroid hormones are present in human milk and are positively correlated with those in serum.

[Indexed for MEDLINE]

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