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Biomed Res Int. 2013;2013:916136. doi: 10.1155/2013/916136. Epub 2013 Jul 25.

Isolation and characterisation of mesenchymal stem cells from different regions of the human umbilical cord.

Author information

1
The Robert Jones and Agnes Hunt Orthopaedic Hospital NHS Foundation Trust & ISTM, Keele University, Oswestry, Shropshire SY10 7AG, UK. claire.mennan@rjah.nhs.uk

Abstract

Umbilical cords as a source of stem cells are of increasing interest for cell therapies as they present little ethical consideration and are reported to contain immune privileged cells which may be suitable for allogeneic based therapies. Mesenchymal stem cells (MSCs) sourced from several different cord regions, including artery, vein, cord lining, and Wharton's jelly, are described in the literature. However, no one study has yet isolated and characterised MSCs from all regions of the same cord to determine the most suitable cells for cell based therapeutics.

PMID:
23984420
PMCID:
PMC3741948
DOI:
10.1155/2013/916136
[Indexed for MEDLINE]
Free PMC Article

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