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Br J Psychiatry. 1990 Jul;157:86-94.

Psychiatric phenomena in Alzheimer's disease. IV: Disorders of behaviour.

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Institute of Psychiatry, De Crespigny Park, Denmark Hill, London.


Out of a sample of 178 patients with AD, aggression was present in 20%, wandering in 19%, binge-eating in 10%, hyperorality in 6%, urinary incontinence in 48%, and sexual disinhibition in 7%. Behavioural abnormalities were greater in those with more severe dementia. Temporallobe atrophy correlated with aggression, and widening of the third ventricle with hyperorality. Features of the Kluver-Bucy syndrome were commonly seen, but the full syndrome occurred in only one subject. Patients with at least one feature of the Kluver-Bucy syndrome had greater temporal-lobe atropy than those without any of the features.

[Indexed for MEDLINE]

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