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Nat Prod Res. 2014;28(4):265-7. doi: 10.1080/14786419.2013.830219. Epub 2013 Aug 25.

Metabolites of Streptomyces sp., an endophytic actinomycete from Alpinia oxyphylla.

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1
a Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, School of Chemical Science and Technology, Yunnan University , Kunming 650091 , P.R. China.

Abstract

Four known compounds had been isolated from the Streptomyces sp. YIM66017, and their structures were elucidated by spectral analysis as 2,6-dimethoxy terephthalic acid (1), yangjinhualine A (2), α-hydroxyacetovanillone (3) and cyclo(Gly-Trp) (4). Compound 1 was isolated from natural resources for the first time, and compounds 2-4 were isolated from streptomycetes for the first time. The 2,2-diphenyl-1-picrylhydrazyl radical-scavenging activity assays showed that 1 showed higher activity than rutin with IC50 of 4.61 μg/mL and 2 showed the activity with IC50 of 57.12 μg/mL.

PMID:
23972103
DOI:
10.1080/14786419.2013.830219
[Indexed for MEDLINE]
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