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J Matern Fetal Neonatal Med. 2015 Nov;28 Suppl 1:2261-4. doi: 10.3109/14767058.2013.796162. Epub 2013 Aug 23.

Low-grade intraventricular hemorrhage: is ultrasound good enough?

Author information

1
a Neonatal Intensive Care Unit and.
2
b Pediatric Neuroradiology Unit , Istituto Giannina Gaslini , Genova , Italy.

Abstract

OBJECTIVE:

To assess diagnostic accuracy of cranial ultrasonography (CUS) in detecting low-grade (i.e. grade I and grade II) germinal matrix hemorrhage-intraventricular hemorrhage (GMH-IVH) in very low birth weight (VLBW) infants.

METHODS:

Among VLBW infants who were admitted to Gaslini Children's Hospital neonatal intensive care unit between January and November 2012, patients who underwent both serial CUS since birth and magnetic resonance susceptibility-weighted imaging (SWI) at term-equivalent age were included in this retrospective study. Diagnostic accuracy of CUS in detecting low-grade GMH-IVH was assessed in terms of sensitivity and specificity by comparing it to SWI, which was used as the gold-standard technique.

RESULTS:

Sixty VLBW infants were included in the study. Sensitivity of CUS in detecting low-grade GMH-IVH was low (60%), whilst specificity was 100%.

CONCLUSIONS:

In the present study, CUS sensitivity in detecting grade I-II GMH-IVH proved to be surprisingly low, in contrast with specificity. In other words, we suggest that low-grade GMH-IVH may be underdiagnosed in VLBW infants when assessed exclusively with CUS.

KEYWORDS:

Brain; IVH; MRI; SWI; germinal matrix hemorrhage; intraventricular hemorrhage; preterm; ultrasound

PMID:
23968243
DOI:
10.3109/14767058.2013.796162
[Indexed for MEDLINE]
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