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MMWR Morb Mortal Wkly Rep. 2013 Aug 23;62(33):666.

Investigational drug available directly from CDC for the treatment of infections with free-living amebae.

Abstract

Infections caused by free-living amebae (FLA) are severe and life-threatening. These infections include primary amebic meningoencephalitis (PAM) caused by Naegleria fowleri and granulomatous amebic encephalitis caused by Balamuthia mandrillaris and Acanthamoeba species. Although several drugs have in vitro activity against FLA, mortality from these infections remains>90% despite treatment with combinations of drugs.

PMID:
23965830
PMCID:
PMC4604798
[Indexed for MEDLINE]
Free PMC Article

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