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J ECT. 2013 Sep;29(3):e36-7. doi: 10.1097/YCT.0b013e31828b3515.

Electroconvulsive therapy and Klinefelter syndrome.

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1
Department of Neurology, the First Affiliated Hospital of Anhui Medical University, Anhui Province, China.

Abstract

Klinefelter syndrome is a common sex chromosome disorder characterized by the presence of 1 or more extra X chromosomes, and the most prevalent karyotype is 47,XXY. Epidemiological studies have showed that patients with Klinefelter syndrome had a significantly increased risk of psychosis. We presented a case of a patient with Klinefelter syndrome who was characterized by psychiatric symptoms. The patients had been refractory to clozapine and sodium valproate, but a remarkable improvement occurred after a cycle of 11 sessions of modified electroconvulsive therapy.

PMID:
23965608
DOI:
10.1097/YCT.0b013e31828b3515
[Indexed for MEDLINE]
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