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Saudi J Ophthalmol. 2013 Jan;27(1):47-9. doi: 10.1016/j.sjopt.2011.10.001. Epub 2011 Oct 10.

Cytomegalovirus-related corneal endotheliitis: A review article.

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Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.


Cytomegalovirus (CMV)-related corneal endotheliitis is an inflammation of the corneal endothelium caused by CMV. It typically presents as coin-shaped keratic precipitates (KPs), with or without corneal edema, in otherwise healthy individuals. It may be associated with anterior uveitis and raised intraocular pressure (IOP). Patients with CMV-related corneal endotheliitis respond to systemic and topical ganciclovir with the use of topical steroid. Making an accurate early diagnosis is crucial in preventing loss of corneal endothelial cells and unnecessary treatment resulting from misdiagnosis in these patients.


Corneal endothelium; Cytomegalovirus; Endotheliitis; Ganciclovir

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