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J Trop Pediatr. 2014 Feb;60(1):40-6. doi: 10.1093/tropej/fmt071. Epub 2013 Aug 20.

Assessment of drinking water fortification with iron plus ascorbic Acid or ascorbic Acid alone in daycare centers as a strategy to control iron-deficiency anemia and iron deficiency: a randomized blind clinical study.

Author information

1
University of Ribeirão Preto, Eugênio Ferrante, 170, Ribeirão Preto - SP - Brazil, CEP 14027-150.

Abstract

OBJECTIVE:

Assess drinking water fortification with iron and/or ascorbic acid as a strategy to control iron-deficiency anemia and iron deficiency.

METHODS:

Randomized blind clinical study, fortifying drinking water to 153 pre-school children during 3 months, with iron and ascorbic acid (A), ascorbic acid (B) or plain water (C). Hemoglobin (Hb), mean corpuscular volume (MCV) and ferritin were measured.

RESULTS:

Within the groups, Hb raised in all three groups, MCV in A and B and ferritin in A. The difference between time points 0 and 1 was significant between A and B for Hb, when A and B were compared with C for MCV and when A was compared with either B or C for ferritin.

CONCLUSIONS:

Water fortification is efficient in controlling iron deficiency and anemia. Iron stores' recovery depends on a more effective offer of iron. Water fortification must be preceded by a careful assessment of the previous nutritional status.

KEYWORDS:

anemia; health education; iron deficiency; nutrition assessment

PMID:
23963460
DOI:
10.1093/tropej/fmt071
[Indexed for MEDLINE]

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